منابع مشابه
Redox redux: protecting the ischemic myocardium.
Cardiac ischemia-reperfusion (I-R) injury occurs upon prompt restoration of blood flow to the ischemic myocardium after an acute myocardial infarction. Interestingly, many of the features of I-R injury are related to impaired mitochondrial signaling and mitochondrial dysfunction. Restoring cardiac energy bioavailability and reduction-oxidation (redox) signaling are therefore important in recove...
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The architecture of the active site of members of the protein tyrosine phosphatase (PTP) superfamily renders these enzymes sensitive to reversible oxidation and inactivation. The importance of reversible oxidation of PTP superfamily members in controlling the signal output following an extracellular stimulus is discussed.
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ROBIN S. WAPLES,∗ PETER B. ADAMS,† JAMES BOHNSACK,‡ AND BARBARA L. TAYLOR§ ∗Northwest Fisheries Science Center, 2725 Montlake Boulevard East, Seattle, WA 98112, U.S.A., email [email protected] †Southwest Fisheries Science Center, 110 Shaffer Road, Santa Cruz, CA 95060, U.S.A. ‡Southeast Fisheries Science Center, 75 Virginia Beach Drive, Miami, FL 33149, U.S.A. §Southwest Fisheries Science C...
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ژورنال
عنوان ژورنال: Nature
سال: 2011
ISSN: 0028-0836,1476-4687
DOI: 10.1038/469476a